Prestorage Leukocyte Reduction with In-Line Filtration of Whole Blood (2)
All counts of white blood cells after filtration were < 1 × 106 per unit. For almost all storage parameters no significant differences were found between leukocyte reduction filters and control units. The plasma fibrinopeptide A values below 30 ng/ml prior to freezing indicate that filtration does not activate the coagulation factors. Furthermore, the filtration did not influence either the biological values or the coagulation factors of plasma units.
Whole blood filtration prior to component preparation seems to offer a useful alternative technique for obtaining leukocyte reduction filters and plasma.
